GENERAL CATALOGUE
Lexibulin
HY-10498 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10498
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Catalog No: HY-10498
CAS No: 917111-44-5
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Lexibulin CYT-997 is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo. Lexibulin induces cell apoptosis and induces mitochondrial ROS generation in GC cells.
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