GENERAL CATALOGUE
LFHP-1c
HY-139598 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-139598
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Manufacturer product page
medchemexpress.com/lfhp-1c.htmlCatalog No: HY-139598
CAS No: 2102347-47-5
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
LFHP-1c is an PGAM5 inhibitor with neuroprotective activity in brain ischemic stroke. LFHP-1c protects blood-brain barrier integrity from ischemia-induced injury. LFHP-1c binds to endothelial PGAM5 to inhibit the activity of PGAM5 phosphatase and the interaction of PGAM5 with NRF2. LFHP-1c exhibits in vitro and in vivo protection.
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