

HY-15340R · 1 mg
MedChemExpress · Cat: HY-15340R
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medchemexpress.com/lg100268-standard.html
Description
LG100268 Standard is the analytical standard of LG100268. This product is intended for research and analytical applications. LG100268 LG268 is a potent, selective and orally active retinoid X receptor RXR agonist with EC50 values of 4 nM, 3 nM, and 4 nM for RXR-?, RXR-?, and RXR-?, respectively. LG100268 displays >1000-fold selectivity for RXR over RAR, the Ki values are 3.4 nM, 6.2 nM and 9.2 nM for RXR-?, RXR-?, and RXR-?, respectively. LG100268 activates RXR homodimers to induce transcriptional activation. LG100268 can be used for the study of lung carcinogenesisy.







