LG190178

Description

LG190178 is a non-steroidal vitamin D receptor VDR ligand that can induce the formation of heterodimer complexes between VDR and retinoid X receptor RXR , stabilizing the agonistic conformation of the VDR ligand-binding domain and promoting its interaction with co-activators. LG190178 has functions in regulating calcium homeostasis, bone mineralization, as well as cell proliferation, differentiation, and apoptosis, making it useful for research in psoriasis, osteoporosis, and cancer.