GENERAL CATALOGUE
LH2-051
HY-161723 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-161723
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Manufacturer product page
medchemexpress.com/lh2-051.htmlCatalog No: HY-161723
CAS No: 2358754-22-8
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
LH2-051, a lysosome-enhancing compound LYEC , is a brain-penetrant dopamine transporter DAT inhibitor Ki: 0.95 ?M . LH2-051 inhibits DAT-mediated dopamine uptake with an IC50 of 3.0 ?M. LH2-051 promotes nuclear translocation of TFEB and lysosome biogenesis. LH2-051 improves the memory of amyloid precursor protein APP /Presenilin 1 PS1 mice. LH2-051 can be used for the study of AlzheimerAAasAasAas disease.
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