GENERAL CATALOGUE
LHF418
HY-161450 · 50 mg
MedChemExpress · Cat: HY-161450
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medchemexpress.com/lhf418.html
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Catalog No: HY-161450
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
LHF418 is an effective SOS1 PROTAC degrader with a DC50 value of 209.4 nM in A549 cells. LHF418 can effectively inhibit RAS signaling and colony formation in KRAS-driven cancer cells. Structural note: Blue: Cereblon ligand HY-A0003 , Black: linker; Pink: SOS1 binder SOS1 Ligand intermediate-3 HY-161452 .
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