GENERAL CATALOGUE
LIB3S0280
HY-172620 · 5 mg
MedChemExpress · Cat: HY-172620
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medchemexpress.com/lib3s0280.html
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Catalog No: HY-172620
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
LIB3S0280 is a potent TBK1 inhibitor with an IC50 value of 493.9 nM. LIB3S0280 exhibits better anticancer effects in pancreatic cancer cell lines with high TBK1 expression. LIB3S0280 inhibits TBK1 downstream signaling pathways, including PI3K/AKT and NF-?B. LIB3S0280 induces G2/M arrest, apoptosis and cellular senescence. LIB3S0280 can be used for pancreatic ductal adenocarcinoma PDAC research.
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