GENERAL CATALOGUE
Licochalcone B
HY-N0373 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N0373
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Catalog No: HY-N0373
CAS No: 58749-23-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid ? 42 self-aggregation IC50=2.16 ?M and disaggregate pre-formed A?42 fibrils, reduce metal-induced A?42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-?B p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7?NLRP3 interaction.
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