Licochalcone B (Standard)

Description

Licochalcone B Standard is the analytical standard of Licochalcone B. This product is intended for research and analytical applications. Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid ? 42 self-aggregation IC50=2.16 ?M and disaggregate pre-formed A?42 fibrils, reduce metal-induced A?42 aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-?B p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7?NLRP3 interaction.