

HY-19344 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-19344
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medchemexpress.com/Lifitegrast.htmlDescription
Lifitegrast SAR 1118 is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 ICAM-1 to lymphocyte function-associated antigen 1 LFA-1 , interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease.