GENERAL CATALOGUE
Ligelizumab
HY-P99300 · 1 mg
MedChemExpress · Cat: HY-P99300
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Catalog No: HY-P99300
CAS No: 1322627-61-1
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
Ligelizumab QGE 031 is a humanized high-affinity anti-immunoglobulin IgE monoclonal antibody. Ligelizumab selectively inhibits the binding of IgE to the high-affinity receptor Fc?RI, while the inhibitory effect on the low-affinity receptor CD23 is weak. Ligelizumab can inhibit the activation of effector cells such as mast cells and Basophil, while reducing the production of IgE by B cells, and restoring the IFN-? production and regulatory T cell Treg induction function of plasmacytoid dendritic cells pDC . Ligelizumab can be used in the study of allergic diseases such as chronic spontaneous urticaria, allergic asthma .
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