Linearmycin A

Description

Linearmycin A is a polyene antibiotic that has been found in Streptomyces. It is active against the bacteria S. aureus and E. coli MICs=3.1 and 1.6 ?g/disc, respectively , the fungi S. cerevisiae and C. albicans MICs=0.1 and 1.6 ?g/disc, respectively , and the plant pathogenic fungus A. niger in disc assays MIC=0.2 ?g/disc . Linearmycin A induces lysis and degradation of B. subtilis as a component of Streptomyces Mg1 extract.