GENERAL CATALOGUE
Linifanib
HY-50751 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-50751
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Catalog No: HY-50751
CAS No: 796967-16-3
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Linifanib ABT-869 is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family with IC50s of 4, 3, 66, and 4 nM for KDR, FLT1, PDGFR?, and FLT3, respectively. Linifanib shows prominent antitumor activity. Linifanib has much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. Linifanib is a specific miR-10b inhibitor that blocks miR-10b biogenesis.
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