Lipoxin B4 methyl ester

Description

Lipoxin B4 LXB4 methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4. LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte PMN migration stimulated by leukotriene B4 LTB4; Item No. 20110 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.