GENERAL CATALOGUE
Liquiritin
HY-N0376 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-N0376
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Catalog No: HY-N0376
CAS No: 551-15-5
Category: Immunology Inflammation
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 ?M, 0.61 ?M, and 3.72?M for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity.
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