GENERAL CATALOGUE
LJI308
HY-19713 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-19713
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medchemexpress.com/LJI308.htmlCatalog No: HY-19713
CAS No: 1627709-94-7
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
LJI308 is a potent pan-ribosomal S6 kinase RSK inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK T359/S363 and YB-1 S102 after irradiation, treatment with EGF, and in cells expressing a KRAS mutation.