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LL-K12-18
GENERAL CATALOGUE

LL-K12-18

HY-163944 · 5 mg

MedChemExpress · Cat: HY-163944

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medchemexpress.com/ll-k12-18.html
Catalog No: HY-163944
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress

Description

LL-K12-18 is a two-site molecular glue that enhances the protein-protein interaction of the CDK12-DDB1 complex, stabilizing the CDK12-DDB1 complex and promoting the degradation of cyclin K EC50=0.37 nM . LL-K12-18 exhibits strong gene transcription inhibition and anti-proliferation effects in tumor cells. LL-K12-18 can be used in cancer research.

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