GENERAL CATALOGUE
LO-3-61
HY-175179 · 50 mg
MedChemExpress · Cat: HY-175179
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Manufacturer product page
medchemexpress.com/lo-3-61.htmlCatalog No: HY-175179
Category: Epigenetics
Pack Size: 50 mg
Brand: MedChemExpress
Description
LO-3-61, a JQ-1 HY-13030 analog bearing a truncated fumaramide handle, is a PROTAC proteolysis-targeting chimeras -like BRD4 degrader. LO-3-61 degrades both the long and short isoforms of BRD4 CUL4DcAr16-dependently in cells. LO-3-61 shows selectivity for BRD3 and BRD4 degradation in MDA-MB-231 cells.
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