GENERAL CATALOGUE
Locostatin
HY-W013411A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-W013411A
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Catalog No: HY-W013411A
CAS No: 90719-30-5
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Locostatin UIC-1005 is a potent RKIP inhibitor. Locostatin binds Raf kinase inhibitor RKIP protein and disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. Locostatin inhibits cell proliferation and migration. Locostatin can be used to synthesize chemical probes toward PEBP-proteins. Locostatin aggravates thioacetamide HY-Y0698 -induced acute liver failure in mice .
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