GENERAL CATALOGUE
Lofepramine hydrochloride
HY-12390A · 50 mg
MedChemExpress · Cat: HY-12390A
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Catalog No: HY-12390A
CAS No: 26786-32-3
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
Lofepramine Lopramine is a modified tricyclic and orally active antidepressant. Lofepramine inhibits the uptake of Noradrenaline NA HY-13715 and 5-hydroxytryptamine 5-HT with IC50s of 2.7 ?M and 11 ?M, respectively. Lofepramine exerts its antidepressant activity by promoting noradrenergic neurotransmission. Lofepramine also enhances serotonergic neurotransmission by inhibiting neuronal uptake of 5-HT and tryptophan pyrrolase. Lofepramine exhibits significant anxiolytic properties. .
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