

HY-75800R · 5 mg
MedChemExpress · Cat: HY-75800R
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Manufacturer product page
medchemexpress.com/lomibuvir-standard.html
Description
Lomibuvir Standard is the analytical standard of Lomibuvir. This product is intended for research and analytical applications. Lomibuvir VX-222 , a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase RdRp with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis.







