GENERAL CATALOGUE
Lon-TK
HY-169436 · 50 mg
MedChemExpress · Cat: HY-169436
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medchemexpress.com/lon-tk.html
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Catalog No: HY-169436
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
Lon-TK is a glycolysis inhibitor + linker conjugate of LTB HY-169434 . LTB is an intelligent responsive prodrug that connects Lonidamine Lon HY-B0486 and a PD-L1 inhibitor BMS-1, HY-19991 through a thioketal linker. It significantly inhibits the glycolytic metabolism of tumor cells and blocks the PD-1/PD-L1 immune escape pathway. Lon-TK shows potential for application in photodynamic-enhanced immunotherapy research.
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