GENERAL CATALOGUE
Lonigutamab
HY-P99712 · 1 mg
MedChemExpress · Cat: HY-P99712
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Catalog No: HY-P99712
CAS No: 2362015-67-4
Category: Antibody-drug Conjugate ADC Related
Pack Size: 1 mg
Brand: MedChemExpress
Description
Lonigutamab hz208F2-4 is a humanized anti-IGF-1R monoclonal antibody, serveing as a targeting vector for antibody-drug conjugates ADCs . Lonigutamab causes G2-M phase cell cycle arrest and increases apoptosis in IGF-1R-overexpressing tumor cells. Lonigutamab demonstrates potent antitumor efficacy in IGF-1R-overexpressing xenograft models. Lonigutamab can be used for the study of Solid tumors with overexpression of IGF-1R and thyroid eye diseasessup> 2 .
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