Lornoxicam

Description

Lornoxicam Chlortenoxicam is an orally active oxycontin nonsteroidal anti-inflammatory drug NSAID with analgesic, anti-inflammatory, antipyretic and anticancer activities. Lornoxicam exhibits good inhibitory effects on both COX-1 and COX-2 COX-1: IC50=0.005 ?M; COX-2:IC50=0.008 ?M and inhibits the production of NO by iNOS IC50=65 ?M and the proinflammatory cytokine IL-6 IC50=54 ?M . Lornoxicam also inhibits tumor cell proliferation and migration and induces tumor cell apoptosis. Lornoxicam can be used in the study of inflammatory pain, colorectal cancer and breast cancer.