GENERAL CATALOGUE
LP-935509
HY-117626 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-117626
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medchemexpress.com/lp-935509.htmlCatalog No: HY-117626
CAS No: 1454555-29-3
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
LP-935509 is an orally active, potent, selective, ATP-competitive and brain-penetrant inhibitor of adaptor protein-2 associated kinase 1 AAK1 with an IC50 of 3.3 nM and a Ki of 0.9 nM, respectively. LP-935509 is also a potent inhibitor of BIKE IC50=14 nM and a modest inhibitor of GAK IC50=320 nM . LP-935509 shows antinociceptive activity. LP-935509 can be used for neuropathic pain and SARS-CoV-2 research.