Lunarine

Description

Lunarine is an alkaloid, which can be isolated from the seeds of kale Lunaria annua . Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD50 of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase TryR with Ki of 304 ?M.