

HY-170027 · 50 mg
MedChemExpress · Cat: HY-170027
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Manufacturer product page
medchemexpress.com/lw1564.html
Description
LW1564 is an inhibitor for HIF-1? with an IC50 of 1.2 AAasAasAAmuM in HepG2. LW1564 inhibits mitochondrial respiration, reduces ATP production, stimulates HIF-1? degradation, and inhibits proliferation of various cancer cells with GI50 of 0.4-4.6 ?M. LW1564 activates AMPK signaling pathway and inhibits lipid synthesis. LW1564 exhibits antitumor in HepG2 xenograft mouse model.

