GENERAL CATALOGUE
LX1
HY-163940 · 5 mg
MedChemExpress · Cat: HY-163940
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medchemexpress.com/lx1.html
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Catalog No: HY-163940
CAS No: 2647877-84-5
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
LX1 is an anti-prostate cancer compound that targets androgen receptor AR , AR variants and steroidogenic enzyme AKR1C3. LX1 inhibits the enzymatic activity of AKR1C3, reduces the conversion of androstenedione to testosterone and reduces the expression of AR and AR-V7 and downregulates their target genes. LX1 overcomes the resistance of tumor cells to Enzalutamide HY-70002 , and the combination with Enzalutamide HY-70002 further inhibits tumor growth.
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