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LXR? agonist 1
GENERAL CATALOGUE

LXR? agonist 1

HY-173393 · 50 mg

MedChemExpress · Cat: HY-173393

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Catalog No: HY-173393
CAS No: 1790089-97-2
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress

Description

LXR? agonist 1 Compound 40 is a selective LXR? agonist EC50: 42 nM . LXR? agonist 1 also has a certain agonistic effect on LXR? EC50: 266 nM . LXR? agonist 1 promotes target gene transcription by stabilizing the ligand binding domain LBD of LXR?. LXR? agonist 1 exhibits potent antitumor effects in hepatocellular carcinoma cells when combined with the Raf inhibitor Sorafenib HY-10201 . LXR? agonist 1 can be used in the study of lipotoxic cancers.

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