LXY3

Description

LXY3 LXY2 is a VLA-3-blocking peptide that inhibits the interaction between integrin ?3?1 VLA-3 on neutrophil surfaces and laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is used to block neutrophil-mediated nanoparticle release from perivascular pools into the tumor interstitium. LXY3 is commonly employed for targeted imaging of breast cancer.