GENERAL CATALOGUE
LY-2624587
HY-P991656 · 1 mg
MedChemExpress · Cat: HY-P991656
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Manufacturer product page
medchemexpress.com/ly-2624587.htmlCatalog No: HY-P991656
CAS No: 2125546-89-4
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
LY-2624587 is a humanized IgG4 monoclonal antibody antagonist targeting CXCR4. LY-2624587 blocks SDF-1/CXCR4 interaction and SDF-1-induced GTP binding. LY-2624587 significantly inhibits cell migration and induces apoptosis in human lymphoma and leukemia cells. LY-2624587 also inhibits CXCR4 and SDF-1 mediated cell signaling including activation of MAPK and AKT. LY-2624587 can be used for human hematological malignancies like acute myeloid leukemia AML research.
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