GENERAL CATALOGUE
LY1
HY-152101 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-152101
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Catalog No: HY-152101
CAS No: 2883813-32-7
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
LY1 is a potent, selective and covalent inhibitor against both SARS-CoV-2 PLpro and Mpro with Kd values of 1.5 ?M and 2.3 ?M for Mpro C145A protein and PLpro C111A protein, respectively. LY1 potent against the viral proteases, with IC50s of 0.12 ?M and 0.99 ?M against Mpro and PLpro. LY1 shows high selectivity over other kinases, human proteases and metalloenzyme.
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