GENERAL CATALOGUE
LY314228
HY-117792 · 50 mg
MedChemExpress · Cat: HY-117792
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Catalog No: HY-117792
CAS No: 182633-54-1
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
LY314228 is an aminoguanidine 5-HT2 antagonist with relative selectivity for 5-HT2A receptors IC50: 147.9 nM . The Ki values of LY314228 targeting different 5-HT subtypes are 65 nM 5-HT 2A , 1214 nM 5-HT 2B , and 168 nM 5-HT 2C , respectively. LY314228 is an effective inhibitor of 5-HT-induced paw edema in rats with an ED50 of 6.4 mg/kg in ovariectomized female rats..
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