GENERAL CATALOGUE
LY487379
HY-122255 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-122255
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medchemexpress.com/ly487379.htmlCatalog No: HY-122255
CAS No: 353231-17-1
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
LY487379 is a selective human mGluR2 positive allosteric modulator PAM . LY487379 potentiates glutamate-stimulated 35S GTP?S binding with EC50 values of 1.7 ?M and >10 ?M for mGlu2 and mGlu3 receptors respectively. LY487379 promotes cognitive flexibility and facilitates behavioral inhibition in a rat model. LY487379 can be used for schizophrenia research.