GENERAL CATALOGUE
LY487379 hydrochloride
HY-103552 · 5 mg
MedChemExpress · Cat: HY-103552
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medchemexpress.com/ly487379-hydrochloride.htmlCatalog No: HY-103552
CAS No: 353229-59-1
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
LY487379 hydrochloride is a selective human mGluR2 positive allosteric modulator PAM . LY487379 hydrochloride potentiates glutamate-stimulated 35S GTP?S binding with EC50 values of 1.7 ?M and >10 ?M for mGlu2 and mGlu3 receptors respectively. LY487379 hydrochloride promotes cognitive flexibility and facilitates behavioral inhibition in a rat model. LY487379 hydrochloride can be used for schizophrenia research.
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