GENERAL CATALOGUE
LYP-IN-4
HY-155848 · 5 mg
MedChemExpress · Cat: HY-155848
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Manufacturer product page
medchemexpress.com/lyp-in-4.htmlCatalog No: HY-155848
Category: Metabolic Enzyme Protease
Pack Size: 5 mg
Brand: MedChemExpress
Description
LYP-IN-4 compound D14 is a reversible and selective inhibitor of lymphotyrosine phosphatase LYP Ki=1.34 ?M, IC50=3.52?M . LYP-IN-4 inhibits LYP to regulate TCR signaling, up-regulates PD-1/PD-L1 expression, and enhance anti-tumor immunity. LYP-IN-4 activates T cells and inhibits M2 macrophage polarization, inhibits tumor growth in MC38 isogenic mouse models.
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