GENERAL CATALOGUE
LZ-07
HY-172590 · 50 mg
MedChemExpress · Cat: HY-172590
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Manufacturer product page
medchemexpress.com/lz-07.htmlCatalog No: HY-172590
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
LZ-07 is a IRAK4 PROTAC degrader DC50 = 1.14 nM . LZ-07 leads to marked suppression of cytokines including IL-6, IL-1?, TNF-?, and IL-10 upon degradation of IRAK4. LZ-07 can be studied in research for autoimmune diseases Pink: IRAK4 ligand HY-172591 ; Blue: CRBN ligand HY-34590 ; Black: linker HY-B0149 ; CRBN ligand + linker: HY-172593 .
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