GENERAL CATALOGUE
m-Chlorophenylbiguanide
HY-121299 · 50 mg
MedChemExpress · Cat: HY-121299
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medchemexpress.com/m-chlorophenylbiguanide.htmlCatalog No: HY-121299
CAS No: 48144-44-1
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
m-Chlorophenylbiguanide mCPBG is a potent high-affinity agonist of the 5-HT3 receptor, exhibiting an inhibitory effect on long-term potentiation LTP in the mossy fiber-CA3 system. mCPBG attenuates the magnitude of LTP at concentrations of 0.3-1 microM, demonstrating its role in modulating synaptic plasticity. Additionally, the impact of mCPBG on LTP is reversible by the GABAA receptor antagonist bicuculline, indicating a connection between its action and GABAergic neurotransmission.
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