GENERAL CATALOGUE
M871
HY-P1130 · 1 mg
MedChemExpress · Cat: HY-P1130
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Catalog No: HY-P1130
CAS No: 908844-75-7
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
M871 Galanin- 2-13 -Glu-His- Pro 3- Ala-Leu 2-Ala-amide is an orally active and selective galanin receptor type 2 GalR2 antagonist. M871 exhibits Ki values of 13.1 nM, 420 nM and >10 ?M for GalR2, GalR1 and GalR3 respectively. M871 relieves the mice allergic rhinitis by reducing IgE production, as well as the number of B cells in tissues. M871 can inhibit the nerve invasion of salivary adenoid cystic carcinoma SACC and alleviate myocardial ischemia-reperfusion injury. M871 can be used for research on GalR2-related diseases such as epilepsy, pain .
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