GENERAL CATALOGUE
MAC glucuronide phenol-linked SN-38
HY-128943 · 1 mg
MedChemExpress · Cat: HY-128943
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medchemexpress.com/ph-susceptible-lactone.htmlCatalog No: HY-128943
CAS No: 2246380-69-6
Category: Antibody-drug Conjugate ADC Related
Pack Size: 1 mg
Brand: MedChemExpress
Description
MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 DNA topoisomerase I inhibitor agent linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively.Albumin-coupled MAC glucosidol-linked SN-38 shows good stability in mouse plasma.
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