GENERAL CATALOGUE
Mal-amide-PEG8-Val-Cit-PAB-PNP
HY-172291 · 50 mg
MedChemExpress · Cat: HY-172291
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medchemexpress.com/mal-amide-peg8-val-cit-pab-pnp.html
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Catalog No: HY-172291
CAS No: 1964490-09-2
Category: Antibody-drug Conjugate ADC Related
Pack Size: 50 mg
Brand: MedChemExpress
Description
Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker featuring a maleimide, a PEG spacer, a Val-Cit dipeptide, a PAB. and a PNP carbonate. Maleimide is a thiol-specific covalent linker which is used to label cysteine residues in proteins while the PNP group acts as a highly activated leaving group. Val-Cit linkers are cleaved by cytoplasmic peptidases.
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