GENERAL CATALOGUE
Malabaricone C
HY-N8518 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-N8518
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medchemexpress.com/malabaricone-c.htmlCatalog No: HY-N8518
CAS No: 63335-25-1
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Malabaricone C is an orally active and noncompetitive sphingomyelin synthase SMS inhibitor with IC50 values of 3 ?M and 1.5 ?M for SMS 1 and SMS 2, respectively. Malabaricone C reduces body weight gain, improves glucose tolerance, and decreases lipid accumulation in the liver, showing significant prevention of high fat diet-induced fatty liver in mice. Malabaricone C has anti-inflammatory effects, which is found in the fruits of Myristica cinnamomea King. Malabaricone C is promising for research of obesity and immunological disorders caused due to hyper-activation of T-cells.
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