

HY-N6796 · 1 mg
MedChemExpress · Cat: HY-N6796
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Manufacturer product page
medchemexpress.com/manumycin-a.html
Description
Manumycin A is a polyketide antibiotic and an inhibitor of thioredoxin reductase 1 TrxR-1 . Manumycin A can inhibit the growth of breast cancer cells and exert its anti-tumor activity through LC3. Manumycin A can downregulate the release of pro-inflammatory cytokines in human monocytes stimulated by TNF ?, and has potential anti-inflammatory activity. Manumycin A can inhibit the Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration resistant prostate cancer cells to suppress exosome biogenesis and secretion.







