

HY-117025 · 1 mg
MedChemExpress · Cat: HY-117025
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medchemexpress.com/manzamine-a.htmlDescription
Manzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3? and CDK-5 with IC50s of 10.2 ?M and 1.5 ?M, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against HSV-1.







