GENERAL CATALOGUE
Manzamine A hydrochloride
HY-117025A · 1 mg
MedChemExpress · Cat: HY-117025A
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medchemexpress.com/manzamine-a-hydrochloride.htmlCatalog No: HY-117025A
CAS No: 104264-80-4
Category: Anti-infection
Pack Size: 1 mg
Brand: MedChemExpress
Description
Manzamine A hydrochloride, an orally active beta-carboline alkaloid, inhibits specifically GSK-3? and CDK-5 with IC50s of 10.2 ?M and 1.5 ?M, respectively. Manzamine A hydrochloride targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A hydrochloride has antimalarial and anticancer activities. Manzamine A hydrochloride also shows potent activity against HSV-1.
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