MAP2K5 Mouse Monoclonal Antibody

Description

EnkiLife offers the MAP2K5 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ELISA,FC application. Alternative Names of Immunogen: MEK5; MAPKK5; PRKMK5; HsT17454. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. Research Area: TGF-beta signaling pathway,MAPK signaling pathway,Jak-STAT signaling pathway