MAP2K6 Mouse Monoclonal Antibody

Description

EnkiLife offers the MAP2K6 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,IHC,ELISA application. Alternative Names of Immunogen: MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; MAP2K6. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000 Background: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas. Research Area: Apoptosis,TGF-beta signaling pathway,MAPK signaling pathway,Jak-STAT signaling pathway