MAP3K7 Mouse Monoclonal Antibody

Description

EnkiLife offers the MAP3K7 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for ELISA application. Alternative Names of Immunogen: TAK1; MEKK7; TGF1a. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ELISA 1:5000-1:20000 Background: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. Research Area: Apoptosis,TGF-beta signaling pathway,MAPK signaling pathway