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Masitinib
GENERAL CATALOGUE

Masitinib

HY-10209 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-10209

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medchemexpress.com/Masitinib.html
Catalog No: HY-10209
CAS No: 790299-79-5
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

Masitinib AB1010 is a potent, orally bioavailable, and selective inhibitor of c-Kit IC50=200 nM for human recombinant c-Kit . It also inhibits PDGFR?/? IC50s=540/800 nM , Lyn IC50= 510 nM for LynB , Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib AB1010 has anti-proliferative, pro-apoptotic activity and low toxicity.

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