GENERAL CATALOGUE
Mavorixafor hydrochloride
HY-50101C · 5 mg
MedChemExpress · Cat: HY-50101C
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Catalog No: HY-50101C
CAS No: 880549-30-4
Category: Anti-infection
Pack Size: 5 mg
Brand: MedChemExpress
Description
Mavorixafor AMD-070 hydrochloride is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor hydrochloride also inhibits the replication of T-tropic HIV-1 NL4.3 strain in MT-4 cells and PBMCs with an IC50 of 1 nM and 9 nM, respectively. Mavorixafor hydrochloride can be used for the study of WHIM syndrome.